Mohammad Waqas¹, Muaz. Arslan¹, M. Asmar¹, Huzifa Khaleelullah, Abdul Hamid Kassab¹, Nezar M. F. Mohammad¹
Chronic Kidney Disease (CKD) is a pressing global health concern with an escalating prevalence, contributing to substantial mortality and morbidity rates. Neurological complications are pervasive in CKD patients,
impacting both the central and peripheral nervous systems (PNS). This spectrum includes cerebrovascular accidents, posterior reversible encephalopathy syndrome, osmotic demyelination syndrome, cerebral infection, sinus vein thrombosis, polyneuropathy, mononeuropathy, and carpal tunnel syndrome, among other manifestations.
Treatments for CKD, such as Hemodialysis (HD), a prevalent intervention, introduce additional neurological complications, including dialysis disequilibrium syndrome, dementia, and cerebrovascular accidents. Collaborative efforts between nephrologists, neurologists, and other specialists are imperative for effective management, alleviating the burden on CKD patients.
The objective of this study is to evaluate and contrast neurological complications among chronic kidney disease (CKD) patients undergoing hemodialysis (HD) and those not undergoing maintenance HD. The results indicate a heightened prevalence of neurological complications in the advanced stages of CKD and among individuals receiving hemodialysis compared to those not undergoing HD. Headache, stroke, seizures, and altered mental state were more commonly observed in patients with advanced CKD and those undergoing hemodialysis. However, no significant relationship was found between hemodialysis and peripheral neuropathy or seizures.
The study underscores the crucial need for early detection, monitoring, and management of neurological complications in CKD patients, particularly in advanced stages and those undergoing HD. Collaborative efforts between healthcare specialists are essential for addressing the multifaceted challenges associated with neurological complications in CKD.
